Traces matter more than weights for agent training at this point; without open trajectories the closed labs just keep extending their lead on agentic behavior even if every frontier model gets open-sourced tomorrow.
RESEARCH
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CRISPR genome editing accessibility and standard care advancement
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How individualized CRISPR genome editing can go from rare, expensive use to broader accessibility and a standard of care
by @UrnovFyodor and Sadik Kassim @Nature https://
nature.com/articles/d4158
6-026-01243-y
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MIT AI-controlled fibers replicate human muscle movement
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MIT researchers just replicated human muscles with AI-controlled fibers.
— Rowan Cheung (@rowancheung) 22 avril 2026
Inside each fiber is a sealed tube of electrically charged liquid and a tiny electric pump.
When the pump activates, one side contracts while the other relaxes, just as your biceps and triceps do when you… pic.twitter.com/3rFCXENoznMIT researchers just replicated human muscles with AI-controlled fibers. Inside each fiber is a sealed tube of electrically charged liquid and a tiny electric pump. When the pump activates, one side contracts while the other relaxes, just as your biceps and triceps do when you
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Sex Chromosomes Impact on Cancer and Neurologic Disease Research
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Our X and Y chromosomes play a bigger part in health than acknowledged, including cancer, autoimmunity, and neurologic conditions. A new @nature feature
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Self-Proclaimed Researcher After Reading One Chalmers Paper
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Missing: guy who has read exactly one Chalmers paper and now considers himself equipped to end the debate.
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Deep Learning from Scratch series reaches LLMs milestone
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Ten years of the "Deep Learning from Scratch" series reaching LLMs is a perspective almost nobody else has, and the build-from-scratch framing is what makes these books age so well.
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27B Dense Model Outperforms 397B MoE on Coding Benchmarks
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A 27B dense model beating the 397B-A17B MoE on coding benchmarks is quite cool, and a better signal than the open-source-catches-closed headline it'll get flattened into.
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AlignedNews.com: AI Community Paper Discovery Platform
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This is why I built https://
alignednews.com/ai so I can find the papers and other things the AI community is sharing -

SASInnovate Digital Pass Free Access to 85+ Hours Content
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Can’t make #SASInnovate in person? Get your free digital pass! Starting April 28, enjoy virtual access to keynotes, expert sessions, live demos and 85+ hours of content to watch live or on demand. It’s a great way to stay connected http://
2.sas.com/6013BBBFrd -

AGI Alpha Demonstrates Recursive Improvement in Controlled Environment
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While others are funding speculative self-improving AI, AGI Alpha is building the first system to prove recursive improvement under controlled conditions. https://
x.com/FT/status/2045
842784033059114
… #AGIALPHA