Top stories in AI today: – Microsoft’s ‘step towards medical superintelligence’
– Baidu open-sources ERNIE 4.5
– Automate YouTube content creation with AI
– Chai Discovery's AI designs working antibodies
– 4 new AI tools & 4 job opportunities Read more: https://
therundown.ai/p/microsoft-st
eps-towards-medical-superintelligence
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OPEN SOURCE
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Microsoft advances medical superintelligence with latest AI breakthroughs
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Multi-LLM AB-MCTS Combination Outperforms on ARC-AGI-2 Benchmark
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The Multi-LLM AB-MCTS combination of o4-mini + Gemini-2.5-Pro + DeepSeek-R1-0528, current frontier AI models, achieves strong performance on the ARC-AGI-2 benchmark, outperforming individual models by a large margin. Implementation of AB-MCTS on GitHub: https://
github.com/SakanaAI/treeq
uest
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Baidu Open-Sources 10 ERNIE 4.5 Model Versions, 424B Beats DeepSeek V3
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Baidu open-sourced 10 versions of its ERNIE 4.5 model family. Key highlights: —Models from 300M to 424B params
—424B version beats DeepSeek V3 on 22/28 benchmarks
—“Heterogeneous” training architecture for increased efficiency
—Apache 2.0 license -
Open-Source AI Models Struggle to Match Closed Competitors
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had the depressing realization that since chatGPT came out, there has *never* been a moment when the best model was open-source the open models just never quite manage to catch up to closed ones before the the next one drops
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Scira: Developer-Built Search Alternative to Perplexity
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9/ Try Scira: https://
scira.ai GitHub: https://
github.com/zaidmukaddam/s
cira
… Follow Zaid: @zaidmukaddam This isn’t just a Perplexity alternative. It’s what happens when one developer decides to build what the rest of us were waiting for. -
Scira: Full-Stack AI Search Engine Reaches 1 Million Searches Monthly
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7/ Today, Scira is a full-stack AI search engine used by 60,000+ people each month, with more than 1 million searches served. The GitHub repo has earned 8,000+ stars and continues to climb. Built in public. Maintained solo. Proven by use, not hype.
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Scira: From 500 to 16,000 Daily Users in December
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In December, Scira's daily traffic jumped from 500 to 16,000 overnight. His GitHub repo surged from 1K to 6K stars in just a few weeks. People weren't just curious. They were using it.
He renamed it Scira. And just like that, it had momentum. -
Zaid’s Journey Building a Better AI-Powered Web Search Tool
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2/ Like many great dev stories, it started with frustration. Zaid wanted a better way to search across the web using AI. Something fast, clean, and customizable. Perplexity was powerful, but felt closed and out of reach. So he started building.
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MiniPerplx: Open-Source Search with Research Groups Feature
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3/
— Groq Inc (@GroqInc) 30 juin 2025
He called it “MiniPerplx” at first: a lightweight, open-source alternative. No login. No paywall. No noise.
Then he added Research Groups which allowed search across YouTube, Reddit, and X, all at once, grouped by source. It actually worked. That’s when it took off. pic.twitter.com/Jitwo8ad9F3/ He called it “MiniPerplx” at first: a lightweight, open-source alternative. No login. No paywall. No noise. Then he added Research Groups which allowed search across YouTube, Reddit, and X, all at once, grouped by source. It actually worked. That’s when it took off.
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Solo founder builds open-source Perplexity competitor without funding
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This solo founder built an open-source competitor to Perplexity with no team, no funding, and no permission. What started as a weekend project now powers over 1M searches, with 60K+ monthly users. This is the story of @sciraai and how Zaid Mukaddam built what others wouldn’t.