"With Chai-1, we delivered the ability to see the structure of molecules. Now with Chai-2, we have unlocked the ability to design and create them." Wow
GENERATIVE AI
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Connecting MCPs to GPTs with Custom Actions Guide
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Connecting MCPs to GPTs with custom actions is much harder than it needs to be, we wrote up a guide here for it:
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Using Codex AI to Ship Blog Enhancements from Mobile
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I use Codex from my phone pretty often – I've shipped a bunch of enhancements to my blog that way https://
github.com/simonw/simonwi
llisonblog/pulls?q=ispr+isclosed+labelcodex
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GPT-OSS Architectural Innovations in Transformers Library
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GPT‑OSS: Key Architectural Innovations (OpenAI x Hugging Face)
Exploring the core architectural design behind GPT‑OSS, now integrated into Transformers — optimized for efficient reasoning, streaming, and long-context performance. Summary of Innovations: Sliding -
GPT-OSS-120B Open Source Model Now Available on Poe
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Hosted by @TogetherCompute
, you can try gpt-oss-120b at https://
poe.com/GPT-OSS-120B-T and across all platforms. This model is also available via our new API. (2/2) -

OpenAI Releases gpt-oss-120b Open-Source Model on Poe
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OpenAI's new gpt-oss is now on Poe! gpt-oss-120b is a state-of-the-art open-source model that delivers exceptional performance in complex reasoning, multi-step problem-solving, and analysis. (1/2)
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Synthetic Data Quality Reduces Compute Requirements
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Do you think the synthetic data is relevant here? What I mean is that some effective compute has been embedded into the data to generate these high quality tokens, so you don't need as much compute to get value out of them
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Sam Altman’s AI Model Ambitions Lack Self-Awareness
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sam altman wants to build a model that’s rated 3200 on codeforces but has no idea who Sam Altman is and i think that’s beautiful
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Claude System Prompt Connection Philosophy Explored
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My favorite part of the Claude system prompt is how it ends: "Claude is now being connected with a person."
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GPT-OSS Model Performance: Coding Excellence Mixed with Factual Hallucinations
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i’ve spent the last couple hours talking to gpt-oss and can safely say it’s unlike any model i’ve tested one second it’s coding for me at a professional level, the next it’s making up basic facts and clinging to them no matter what i say something very strange is going on