How digital twins and in silico clinical trials can change the future of drug development https://
nature.com/articles/s4159
1-026-04344-3
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@erictopol
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Digital twins and in silico trials revolutionize drug development
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AI and Healthspan Interview with Leading Medical Experts
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My interview on healthspan and AI with @mmlederman1 and @LCalabreseDO @paijournal transcript video https://
youtube.com/watch?v=QXga7d
pvmk8
… https://
paijournal.com/index.php/paij
ournal/article/view/1028
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Medical AI Lacks Evidence for Improving Patient Care
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On the lack of compelling evidence that medical AI is improving patient care, and what to do about it, a @NatureMedicine editorial https://
nature.com/articles/s4159
1-026-04389-4
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Editorial calls for stricter AI regulation in healthcare
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An editorial by @HashemZikry @latimes @counselheatlh calling for more regulation of AI for patient use. Yes, there is "the staggering weight of unmet medical need," 1/3 Americans are using it to "diagnose symptoms and direct care," and states are moving in different directions.
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We Are All Genetic Mosaics: Understanding Human Genetic Variation
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And much more.
It's open-access. All content on Ground Truths— podcasts and analyses— is free. Subscribe.
Link to the new post https://
erictopol.substack.com/p/we-are-all-g
enetic-mosaics
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Pulsed Field Ablation Outperforms Medical Therapy for Atrial Fibrillation
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New @NEJM For persistent atrial fibrillation, first-line pulsed field ablation (PFA) superior to medical therapy (AAD) in a randomized trial for preventing recurrent atrial arrhythmias @omwazni https://
nejm.org/doi/full/10.10
56/NEJMoa2600929?query=featured_home
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Research advances in healthcare and medical science applications
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2 support pieces https://
thelancet.com/journals/lance
t/article/PIIS0140-6736(26)00659-8/abstract
… https://
nature.com/articles/s4159
1-026-04389-4
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Medical imaging AI proves effective but LLMs lack real world evidence
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Superhuman interpretation AI for medical images, such as mammography and endoscopy, has been proven to improve diagnostic accuracy in multiple randomized trials but mostly not implemented. But LLMs for clinical decision support have little real world medicine proof, but are
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CDC Crisis: Editorial in The Lancet Examines Public Health Agency
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The CDC is on the Brink, the editorial in this week's @TheLancet https://
thelancet.com/journals/lance
t/article/PIIS0140-6736(26)00799-3/fulltext
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CGM AI Superior to Self-Monitoring for Type 2 Diabetes Control
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A randomized trial of continuous glucose monitoring (CGM) vs self-monitoring for Type 2 diabetes on basal insulin and drug therapies shows superiority of CGM for gluocse regulation https://
thelancet.com/journals/landi
a/article/PIIS2213-8587(26)00076-8/fulltext
… @TheLancetEndo