As we have previously noted in multiple studies, an AI model alone outperformed physicians with AI (GPT-4) for multiple tasks @pranavrajpurkar https://
nytimes.com/2025/02/02/opi
nion/ai-doctors-medicine.html
… https://
erictopol.substack.com/p/when-doctors
-with-ai-are-outperformed
…
@erictopol
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AI Alone Outperforms Doctors Using AI in Multiple Tasks
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OpenAI o1 Outperforms GPT-4 and Physicians in Clinical Triage
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New @ScienceMagazine The o-1 reasoning model (text only, from @OpenAI
, released, Sept 2024) exceeded performance cf GPT-4 and physicians for clinical vignette management reasoning and in a real-world emergency department assessment for initial triage @AdamRodmanMD -
AI Advances Prediction of Type 1 Autoimmune Diabetes
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A jump in our ability to predict Type 1 autoimmune diabetes should help future preventive strategies @NatureGenet https://
nature.com/articles/s4158
8-026-02571-5
… https://
nature.com/articles/s4158
8-026-02578-y
… -
Organs Age Differently: Plasma Proteins Track Individual Aging Rates
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Our organs age at a different pace intra-individual, as tracked through plasma proteins. Now confirmed for female reproductive organs @NatureAging https://
nature.com/articles/s4358
7-026-01098-y
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AI in Medicine: Burial and Excavation Commentary
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The burial and the excavation @JAMA_current commentary today https://
jamanetwork.com/journals/jama/
fullarticle/2848376
…
(what I wrote about in Deep Medicine, 2019) -
Polygenic Risk Scores Cardiovascular AI Clinical Implementation Gap
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Polygenic risk scores for 8 cardiovascular traits in both @MassGenBrigham and @AllofUsResearch
—superimposable— strongly indicate risk. Yet still not implemented in clinical practice https://
jacc.org/doi/10.1016/j.
jacc.2026.03.035
… -
Neurons Hijacking in Cancer: Neural Fibers Slow Melanoma Growth
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A twist in cancer neuroscience with many studies showing hijacking of neurons to promote cancer—melanoma growth slowed by nerve fibers in skin https://
cell.com/neuron/fulltex
t/S0896-6273(26)00285-0
… -
AI Detects Pancreatic Cancer Better Than Radiologists
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An AI that detects occult pancreatic cancer better than radiologists (73 vs 39%) via CT with external validation https://
gut.bmj.com/content/early/
2026/04/22/gutjnl-2025-337266
… -
AI Mental Health Support Shows Promise in Real-World Study
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Some AI progress for mental health support seen in a real-world prospective study (<-there are few of these)
"In a real-world, two-arm prospective study, resident psychiatrists assisted by PsychFound demonstrated higher consultation quality, higher diagnostic accuracy, more -
TED Talk on Retinal Information Processing in AI Vision
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I gave a @TEDTalks on this topic, and the richness of information from the retina keeps expanding