What superhuman vision can detect from the retinal photo, which human eyes cannot, is stunning. A new foundation AI model screening for diabetes hypertension, hyperlipidemia, gout, osteoporosis, and thyroid disease @NatureMedicine https://
nature.com/articles/s4159
1-026-04359-w
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@erictopol
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AI Foundation Model Detects Multiple Diseases from Retinal Photos
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Gene Therapy Eye Trial Begins: First Clinical Test Underway
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We don't even know if it will work in the eye, the first small pilot trial yet to start, by @heidiledford @Nature https://
nature.com/articles/d4158
6-026-01024-7
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Accidental Medical Discoveries: Serendipity in Healthcare Innovation
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Big innovations that were discovered by mistake!
Nice summary by @Zlatimeyer Can add coronary angiography by Mason Sones to the list, and many others in medicine.
Gift link https://
wsj.com/business/us-in
ventions-mistake-discovery-8d0ff716?st=WkraPi&reflink=desktopwebshare_permalink
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Obesity’s Epigenetic Impact on Immune System Memory
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The impact oif obesity on the immune system.
Through methylation, obesity imprints memory to CD4+ (helper) T cells, which can last for many years, and promotes immune system dysregulation and inflammation. @emboreports https://
link.springer.com/article/10.103
8/s44319-026-00765-w
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Digital twins and in silico trials revolutionize drug development
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How digital twins and in silico clinical trials can change the future of drug development https://
nature.com/articles/s4159
1-026-04344-3
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AI and Healthspan Interview with Leading Medical Experts
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My interview on healthspan and AI with @mmlederman1 and @LCalabreseDO @paijournal transcript video https://
youtube.com/watch?v=QXga7d
pvmk8
… https://
paijournal.com/index.php/paij
ournal/article/view/1028
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Medical AI Lacks Evidence for Improving Patient Care
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On the lack of compelling evidence that medical AI is improving patient care, and what to do about it, a @NatureMedicine editorial https://
nature.com/articles/s4159
1-026-04389-4
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Editorial calls for stricter AI regulation in healthcare
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An editorial by @HashemZikry @latimes @counselheatlh calling for more regulation of AI for patient use. Yes, there is "the staggering weight of unmet medical need," 1/3 Americans are using it to "diagnose symptoms and direct care," and states are moving in different directions.
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We Are All Genetic Mosaics: Understanding Human Genetic Variation
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And much more.
It's open-access. All content on Ground Truths— podcasts and analyses— is free. Subscribe.
Link to the new post https://
erictopol.substack.com/p/we-are-all-g
enetic-mosaics
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Pulsed Field Ablation Outperforms Medical Therapy for Atrial Fibrillation
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New @NEJM For persistent atrial fibrillation, first-line pulsed field ablation (PFA) superior to medical therapy (AAD) in a randomized trial for preventing recurrent atrial arrhythmias @omwazni https://
nejm.org/doi/full/10.10
56/NEJMoa2600929?query=featured_home
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