We could pick up risk of cancer and detect it much earlier if we applied LLMs to electronic health records, as shown in this @AllofUsResearch study
@erictopol
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AI detects osteoporosis from retinal images in new study
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Our retina image is so rich with information, a gateway to the whole body, well beyond the eye. Today add osteoporosis to the list. https://
journals.plos.org/digitalhealth/
article?id=10.1371/journal.pdig.0001360&utm_source=pr&utm_medium=email&utm_campaign=plos006
…
This adds to what I recently wrote about at Ground Truths https://
erictopol.substack.com/p/the-paradox-
of-medical-ai-implementation
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Multimodal AI outperforms physicians in simulated study
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A multimodal AI (AIME) had superior performance compared with 18 physicians for almost every metric (29 of 32 axes). Randomized, but simulated, not real-world clinical practice. @GoogleDeepMind @alan_karthi @RyutaroTanno https://
nature.com/articles/s4159
1-026-04371-0
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LLMs’ Uncertainty in Medical AI Debate
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Expressing uncertainty is a major weak spot of LLMs in medicine @NEJM "Can AI Say I Don't Know?"
Good lines: "Contemporary LLMs have passed many
Turing tests, but will they pass this modern test of not knowing? We don’t know." https://
nejm.org/doi/full/10.10
56/NEJMp2517624?query=WB
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AI summaries reduce physician burnout in hospitals
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Agentic AI summaries of hospitalizations were safe and reduced data clerk burden, burnout, and improved sense of well-being for physicians in a prospective study
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AI’s Extensive Impact on Surgical Workflows
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The impact of AI for surgery (pre-op, intraop, post-op) is going to be extensive
A new review https://
frontiersin.org/journals/scien
ce/articles/10.3389/fsci.2026.1783803/full
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Our previous review @NatureMedicine https://
nature.com/articles/s4159
1-024-02970-3
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The Agentic Era Begins: Discover Cutting-Edge AI Tools
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We're seeing major advances vs pancreatic cancer. Today @NEJM data for daraxonrasib @RevMedicines https://
nejm.org/doi/full/10.10
56/NEJMoa2505783?query=featured_home
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Context for this first-in-class molecular glue https://
nejm.org/doi/full/10.10
56/NEJMoa2505783?query=featured_home
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OpenOwl: GUI Automation Agent for AI Assistants
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Such an important study that has huge potential impact vs cancer
✓out the great thread by @AaronNewmanLab -
ElevenLabs Marketplace Empowers Creators with Monetization for AI Music
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OK. Drugs companies are required to provide risks during their TV ads. Why not MRI imaging for healthy individuals, particularly when not a single professional society support their use?
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Gamma AI transforms presentations into a design engine with 3 major upgrades
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Six (yes, 6) college football players with non-concussive head injury (NHI) and changes in their gut microbiome. No controls. What can you conclude from this? Not this:
"Our results provide strong evidence for a link between NHIs and changes in the diversity and composition of