The 2 new clinical trials https://
science.org/doi/10.1126/sc
ience.ade8520
… https://
science.org/doi/10.1126/sc
ience.adf1329
… @divijmathew @andyjminn @EJohnWherry @Teijaro_Lab
@erictopol
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Two New Clinical Trials Published in Science Journal
By
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Armored CAR T cells advance cancer immunotherapy with IL-18
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We're familiar w/engineered T cells, known as CAR
Now there's Armored CAR! https://
eurekalert.org/news-releases/
1046435
… “We’ve likened this CAR T to an armored truck or tank because the release of IL 18 further protects the CAR T cells and promotes their ability to attack the cancer -
AI Breakthrough Improves Lung Cancer Survival Rates Significantly
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60% vs 8% 5-year progression-free survival (PFS). A breakthrough for a type of advanced lung cancer. https://
ascopubs.org/doi/pdf/10.120
0/JCO.24.00581
… @JCO_ASCO @ASCO @bensolomon1 -
SGLT2 Drugs Extend Lifespan via Senescent Cell Clearance
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SGLT2 drugs reduce mortality but we didn't know why. Maybe because they are senolytic, enhancing the clearance of senescent "zombie" cells https://
nature.com/articles/s4358
7-024-00642-y
… @NatureAging Lifespan in mouse model extended by this drug, not by glucose control @NatureAging -
Comprehensive Review on AI Healthcare Applications Published
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Yet more proof here to add to the comprehensive review by @trishgreenhalgh and colleagues below https://
thelancet.com/journals/ebiom
/article/PIIS2352-3964(24)00192-0/fulltext
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AI Detects Heart Artery Inflammation Without Atherosclerotic Narrowing
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Inflammation of the heart arteries in people without obstructive atherosclerotic narrowings or calcification significantly adds to risk assessment for cardiovascular death https://
thelancet.com/journals/lance
t/article/PIIS0140-6736(24)00596-8/fulltext
… @TheLancet FAI-fat attenuation index from CT image -
LLM Deception: A Master Review with Potential Solutions
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LLM #AI, a master of deception
A review @Patterns_CP w/ potential solutions https://
cell.com/patterns/fullt
ext/S2666-3899(24)00103-X?_returnURL=httpslinkinghub.elsevier.comretrievepiiS266638992400103Xshowalltrue
…
by @peter_j_park @MIT @hendrycks @aidanogara_ http://
safe.ai -
Low-field MRI with deep learning transforms affordable point-of-care imaging
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How low field MRI (0.05 Tesla) with deep learning #AI is transforming this imaging to low cost, point of care, with high resolution @ScienceMagazine https://
science.org/doi/10.1126/sc
ience.adm7168https://www.science.org/doi/10.1126/science.adp0670
… -
AI detects diabetes and cardiovascular risk from chest X-ray imaging
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"Your chest x-ray indicates that you may have type 2 diabetes, your coronary calcium score is 976, your ejection fraction is normal, and your 10-year cardiovascular risk of a heart attack, stroke, or death from cardiovascular disease is 14·1%. Please review with your