Link https://
erictopol.substack.com/p/new-anti-agi
ng-evidence-for-estrogen
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@erictopol
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New Anti-Aging Evidence for Estrogen Discovered
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Data Context Problems: Critical AI Challenge
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Exactly. That's a big problem in context with the data
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Polygenic Risk Scores Prove Critical for Heart Disease Prediction
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Hardly anyone knows their polygenic risk score for heart disease and here's yet another study to show how important it is for predicting a person's risk.
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Human Somatic Mutation Mosaicism Exceeds Quadrillions
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We are all somatic mutation mosaics.
"There are trillions of cells in a human body and so the total number of somatic mutations acquired in a single individual may well exceed quadrillions, millions of times the size of the human genome." @Nature https://
nature.com/articles/s4158
6-025-09096-7
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Clonal hematopoiesis shows potential benefit against Alzheimer’s disease
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Clonal hematopoiesis (CH, blood stem cells with mutations) is considered a risk factor for cardiovascular disease and other adverse health outcomes. But today we learn about its potential benefit vs Alzheimer's disease https://
sciencedirect.com/science/articl
e/pii/S1934590925002280?viaihub
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Multimodal AI Predicts Sudden Death Risk in Cardiomyopathy
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Hypertrophic cardiomyopathy carries some risk of sudden death but it is hard to predict who is at high-risk for an implantable cardioverter-defibrillator (ICD). Enter multimodal A.I. https://
nature.com/articles/s4416
1-025-00679-1
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Plasma protein assays enable discovery of cancer biomarkers
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Now that we can assay thousands of plasma proteins in 1-2 ml of blood, there's discovery of many new cancer biomarkers
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AI-Powered Cancer Vaccines Show Promise in Treatment Prevention
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Yes. The time is now. Vaccines to treat and prevent cancer. https://
jci.org/articles/view/
195673
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AI-Generated Podcasts Potential for Science Communication
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On gen A.I. generated podcasts and their potential to foster science communication https://
academic.oup.com/eurjcn/advance
-article/doi/10.1093/eurjcn/zvaf074/8161719#google_vignette
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TREM-2 Protection Mechanism: Immunological Insights for AI Healthcare
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The TREM-2 mechanism of protection