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  • AI for Science: Periodic Labs Launches Autonomous Scientific Discovery Platform
    AI for Science: Periodic Labs Launches Autonomous Scientific Discovery Platform

    Bullish, in the coming decades majority of compute will be spent on ai for science William Fedus (@LiamFedus) Today, @ekindogus and I are excited to introduce @periodiclabs. Our goal is to create an AI scientist. Science works by conjecturing how the world might be, running experiments, and learning from the results. Intelligence is necessary, but not sufficient. New knowledge is created when ideas are found to be consistent with reality. And so, at Periodic, we are building AI scientists and the autonomous laboratories for them to operate. Until now, scientific AI advances have come from models trained on the internet. But despite its vastness — it’s still finite (estimates are ~10T text tokens where one English word may be 1-2 tokens). And in recent years the best frontier AI models have fully exhausted it. Researchers seek better use of this data, but as any scientist knows: though re-reading a textbook may give new insights, they eventually need to try their idea to see if it holds. Autonomous labs are central to our strategy. They provide huge amounts of high-quality data (each experiment can produce GBs of data!) that exists nowhere else. They generate valuable negative results which are seldom published. But most importantly, they give our AI scientists the tools to act. We’re starting in the physical sciences. Technological progress is limited by our ability to design the physical world. We’re starting here because experiments have high signal-to-noise and are (relatively) fast, physical simulations effectively model many systems, but more broadly, physics is a verifiable environment. AI has progressed fastest in domains with data and verifiable results – for example, in math and code. Here, nature is the RL environment. One of our goals is to discover superconductors that work at higher temperatures than today's materials. Significant advances could help us create next-generation transportation and build power grids with minimal losses. But this is just one example — if we can automate materials design, we have the potential to accelerate Moore’s Law, space travel, and nuclear fusion. We’re also working to deploy our solutions with industry. As an example, we're helping a semiconductor manufacturer that is facing issues with heat dissipation on their chips. We’re training custom agents for their engineers and researchers to make sense of their experimental data in order to iterate faster. Our founding team co-created ChatGPT, DeepMind’s GNoME, OpenAI’s Operator (now Agent), the neural attention mechanism, MatterGen; have scaled autonomous physics labs; and have contributed to some of the most important materials discoveries of the last decade. We’ve come together to scale up and reimagine how science is done. We’re fortunate to be backed by investors who share our vision, including @a16z who led our $300M round, as well as @Felicis, DST Global, NVentures (NVIDIA’s venture capital arm), @Accel and individuals including @JeffBezos , @eladgil , @ericschmidt, and @JeffDean. Their support will help us grow our team, scale our labs, and develop the first generation of AI scientists. — https://nitter.net/LiamFedus/status/1973055380193431965#m

    → View original post on X — @_jasonwei, 2025-09-30 16:04 UTC

  • MedicBrain Project: AI Applications in Healthcare

    i'm totally not this guy, but i will talk about all it can be done with it on my #MedicBrain project

    → View original post on X — @jessyseonoob

  • GLM 4.5/4.6 Support Coming to Tenstorrent Local Cluster

    i put in a request to get GLM 4.5/4.6 supported with the Tenstorrent team hoping to make that the first local livestream from my Tenstorrent 4x QuietBox Blackhole cluster my Agentic workflows are about to skyrocket, and all locally 🙂

    → View original post on X — @theahmadosman

  • Designing Agentic Loops for AI-Assisted Coding Tools

    One of the new skills required to get the most out of AI-assisted coding tools – Claude Code, Codex CLI, etc – is designing agentic loops: carefully selecting tools to run in a loop to achieve a specified goal. Do this well and you can solve many coding problems with brute force.

    → View original post on X — @simonw

  • GLM-4.6 Released: Best Open Source Agentic Model
    GLM-4.6 Released: Best Open Source Agentic Model

    GLM-4.6 is out i've had early access it's easily the BEST opensource
    Agentic Model out there PERIOD Z AI cooked

    → View original post on X — @theahmadosman

  • GLM 4.6 Released Today

    GLM 4.6 was just released today

    → View original post on X — @rasbt

  • Claude Sonnet 4.5 Now Available in Flowise for Complex Agents

    Claude Sonnet 4.5 – the strongest model for building complex agents, is now available to be used in Flowise!

    → View original post on X — @flowiseai, 2025-09-30 15:01 UTC

  • C1: Generative UI API for Dynamic Interfaces
    C1: Generative UI API for Dynamic Interfaces

    C1 is a Generative UI API that turns your model’s output into adaptive interfaces in real time. No more text dumps. Your AI apps can now render dynamic components – forms, cards, charts – on the fly. Works with any LLM, framework, or MCP server Fully customizable to your

    → View original post on X — @godofprompt

  • AI-Generated Images Now Indistinguishable From Real Photography

    Photo AI is definitely passable as real pics for me now but I'm highly biased (and blind) Back in the Stable Diffusion days 2 years ago, I thought those pics were passable as real too (and they definitely weren't I see now) so you shouldn't listen to me ever Can you find any

    → View original post on X — @levelsio

  • Hyper Realism AI: Improving Image Remix and Virtual Try-On

    Some things that don't work yet with Hyper Realism:
    – remix (img2img)
    – try on clothes
    – hold product But I'll try make them work today!

    → View original post on X — @levelsio