The 2024 @naturemethods of the year Spatial Proteomics https://
nature.com/articles/s4159
2-024-02565-3
…
How It saved lives (Spatial Medicine) https://
erictopol.substack.com/p/the-dawn-of-
spatial-medicine
…
@erictopol
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Spatial Proteomics Named Nature Methods 2024 Innovation
By
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David Sinclair Anti-Aging Business Faces WSJ Credibility Scrutiny
By
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The David Sinclair anti-aging companies story, front page WSJ https://
wsj.com/health/wellnes
s/david-sinclair-reverse-aging-failed-business-8bc4a43d?mod=Searchresults_pos1&page=1
…
"Follow scientists who say Sinclair tends to exaggerate
the findings and implications of age-related research,
tarnishing a nascent field vying for credibility" -
IHME Call to Action: Health Research and Data Analysis
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The call to action, by @IHME_UW https://
thelancet.com/journals/lance
t/article/PIIS0140-6736(24)02372-9/fulltext
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US Life Expectancy Decline Demands Healthcare Innovation Investment
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Forecast of US life expectancy to 2050 vs >200 countries
Declining rank from current low of ~50.
—"alarming trajectory of health challenges in the USA"
—need to invest in "scientific innovation, health-care access, preventive health care, risk exposure reduction, and education." -
Shaking Sensor Enables Real-Time Inflammation Biomarker Monitoring
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Quite an innovation!
Continuous real-time monitoring of inflammation and protein biomarkers in the body with a shaking sensor https://
science.org/doi/10.1126/sc
ience.adn2600https://www.science.org/doi/10.1126/science.adt8928
… @ScienceMagazine @HZargartalebi @NorthwesternU @czbiohub -
Synthetic Gene Circuits Target Tissue-Specific T Cell Therapeutics
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The next frontier of T cell therapeutics when the T also stands for tissue-targeting, such as brain or local immune response, via synthetic gene circuits @ScienceMagazine https://
science.org/doi/10.1126/sc
ience.adl4237
… https://
science.org/doi/10.1126/sc
ience.adl4793
… https://
science.org/doi/10.1126/sc
ience.adt9921
… -
LLM-based agents opportunities and challenges in healthcare medicine
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The opportunities, challenges and outlook for LLM-based agents in medicine and healthcare—our paper published today @NatMachIntell https://
nature.com/articles/s4225
6-024-00944-1
… @jianing_qiu @KyleLam93 @Ara_Darzi @guohao_li @WongTienYin -
Oussama Leads Impactful Clinical Trial Answering Key Question
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So proud of you, Oussama, for leading this impactful trial, getting the answer to such an important dangling question
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Transformer AI Models Transforming World Applications
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How transformer #AI models are transforming by @mims https://
wsj.com/tech/ai/a-powe
rful-ai-breakthrough-is-about-to-transform-the-world-095b81ea?mod=Searchresults_pos6&page=1
… @EvoscaleAI @GoogleDeepMind @physical_int @brian_ichter @hausman_k @nuro @Waymo -
CRISPR Genome Editing Shows Promise for Amyloid Cardiomyopathy
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CRISPR genome editing clicks for amyloid cardiomyopathy. New @NEJM #AHA24 https://
nejm.org/doi/full/10.10
56/NEJMoa2412309
… A Phase 1 study with marked reduction of serum TTR @dr_m_fontana @ucl