The opportunities, challenges and outlook for LLM-based agents in medicine and healthcare—our paper published today @NatMachIntell https://
nature.com/articles/s4225
6-024-00944-1
… @jianing_qiu @KyleLam93 @Ara_Darzi @guohao_li @WongTienYin
@erictopol
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LLM-based agents opportunities and challenges in healthcare medicine
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Oussama Leads Impactful Clinical Trial Answering Key Question
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So proud of you, Oussama, for leading this impactful trial, getting the answer to such an important dangling question
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Transformer AI Models Transforming World Applications
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How transformer #AI models are transforming by @mims https://
wsj.com/tech/ai/a-powe
rful-ai-breakthrough-is-about-to-transform-the-world-095b81ea?mod=Searchresults_pos6&page=1
… @EvoscaleAI @GoogleDeepMind @physical_int @brian_ichter @hausman_k @nuro @Waymo -
CRISPR Genome Editing Shows Promise for Amyloid Cardiomyopathy
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CRISPR genome editing clicks for amyloid cardiomyopathy. New @NEJM #AHA24 https://
nejm.org/doi/full/10.10
56/NEJMoa2412309
… A Phase 1 study with marked reduction of serum TTR @dr_m_fontana @ucl -
AI Shows Growing Promise in Disease Detection Research
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No, but the indications are growing @NatureMedicine https://
nature.com/articles/s4159
1-024-03382-z?utm_source=nm_etoc&utm_medium=email&utm_campaign=toc_41591_30_11&utm_content=20241115
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Tirzepatide Shows Promise in Heart Failure Treatment Study
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Another GLP-1 drug success. Tirzepatide in heart failure with preserved ejection fraction (HFpEF) with longer term follow-up than 2 previous trials with semaglutide https://
nejm.org/doi/full/10.10
56/NEJMoa2410027
… @NEJM #AHA24
in people with BMI >30; no data yet for HFpEF in people without obesity -
ChatGPT Applied to DNA Analysis: Expert Explanation
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ChatGPT for DNA
good explainer @ScienceMagazine -
Gut microbiome research reveals disease associations and causal mechanisms
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Two important papers on the gut microbiome and disease
—The fecal microbial load is a key determinant confounding prior reports of association with diseases https://
cell.com/cell/fulltext/
S0092-8674(24)01204-2
… @CellCellPress @embl —Innovative approaches to establish causality and mechanisms -
US Obesity Forecast: 250 Million by 2050
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New @TheLancet Obesity in the US now and the forecast
"If the current pattern continues, more than 250 million people living in the USA will have overweight or obesity by 2050." https://
thelancet.com/journals/lance
t/article/PIIS0140-6736(24)01548-4/fulltext
… @IHME_UW -
Spatial Medicine: AI’s Revolutionary Role in Healthcare Innovation
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Link to my post about all of this https://
erictopol.substack.com/p/the-dawn-of-
spatial-medicine
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