The upside of #AI hallucination gift link https://
nytimes.com/2024/12/23/sci
ence/ai-hallucinations-science.html?unlocked_article_code=1.j04.dJai.yeEAdu9_jlQn&smid=url-share
…
by @WilliamJBroad @NYTScience
@erictopol
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The upside of AI hallucination in scientific research
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AI breakthrough enables insulin-free diabetes management in young woman
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Good summary of this important advance in a 25-year-old woman with Type 1 diabetes -> insulin-free
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Brain-Immune System Axis: Three Rheostats for Control
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Featuring 3 different rheostats that can dial up or down the brain-body immune system axis. One of them is from this week's @ScienceMagazine https://
science.org/doi/10.1126/sc
ience.adl4237
… https://
erictopol.substack.com/p/guardians-of
-the-brain
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Deep Visual Proteomics Enables Breakthrough Treatment for Toxic Epidermal Necrolysis
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Commentary by @NordmannThierry @labs_mann @MundAndreas on Deep Visual Proteomics, the transformative innovation used to identify a successful treatment for patients with toxic epidermal necrolysis
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Spatial Proteomics Named Nature Methods 2024 Innovation
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The 2024 @naturemethods of the year Spatial Proteomics https://
nature.com/articles/s4159
2-024-02565-3
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How It saved lives (Spatial Medicine) https://
erictopol.substack.com/p/the-dawn-of-
spatial-medicine
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David Sinclair Anti-Aging Business Faces WSJ Credibility Scrutiny
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The David Sinclair anti-aging companies story, front page WSJ https://
wsj.com/health/wellnes
s/david-sinclair-reverse-aging-failed-business-8bc4a43d?mod=Searchresults_pos1&page=1
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"Follow scientists who say Sinclair tends to exaggerate
the findings and implications of age-related research,
tarnishing a nascent field vying for credibility" -
IHME Call to Action: Health Research and Data Analysis
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The call to action, by @IHME_UW https://
thelancet.com/journals/lance
t/article/PIIS0140-6736(24)02372-9/fulltext
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US Life Expectancy Decline Demands Healthcare Innovation Investment
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Forecast of US life expectancy to 2050 vs >200 countries
Declining rank from current low of ~50.
—"alarming trajectory of health challenges in the USA"
—need to invest in "scientific innovation, health-care access, preventive health care, risk exposure reduction, and education." -

Shaking Sensor Enables Real-Time Inflammation Biomarker Monitoring
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Quite an innovation!
Continuous real-time monitoring of inflammation and protein biomarkers in the body with a shaking sensor https://
science.org/doi/10.1126/sc
ience.adn2600https://www.science.org/doi/10.1126/science.adt8928
… @ScienceMagazine @HZargartalebi @NorthwesternU @czbiohub -
Synthetic Gene Circuits Target Tissue-Specific T Cell Therapeutics
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The next frontier of T cell therapeutics when the T also stands for tissue-targeting, such as brain or local immune response, via synthetic gene circuits @ScienceMagazine https://
science.org/doi/10.1126/sc
ience.adl4237
… https://
science.org/doi/10.1126/sc
ience.adl4793
… https://
science.org/doi/10.1126/sc
ience.adt9921
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