Identifying and validating 7 organ clocks based on MRI
@erictopol
-
Record ultra-rapid genome sequencing AI interpretation for critical patients
By
–
A new world record for ultra rapid whole genome sequencing and interpretation for critically ill individuals @NEJM <4hrs
-
Genome editing advances for mitochondrial disease treatment
By
–
Towards genome editing for mitochondrial diseases https://
nature.com/articles/d4158
6-025-03307-x
… -
Stem cells show promise treating Parkinson’s disease in clinical study
By
–
More progress with stem cells treating #Parkinsons disease, as seen by motor improvements in a dose-escalating study of 12 patients https://
cell.com/cell/fulltext/
S0092-8674(25)01041-4
… -
Preparing Physicians for the Generative AI Era
By
–
A concise viewpoint on how physicians can prepare for the generative A.I. era https://
jamanetwork.com/journals/jamai
nternalmedicine/fullarticle/2840192
… @JAMAInternalMed -
Gene therapy restores hearing in deaf children via one-shot treatment
By
–
New @NEJM One-shot gene therapy for a type of congenital deafness enabled some children to hear for the first time, and 3 of 12 kids achieved normal hearing http://
nejm.org/doi/full/10.10
56/NEJMoa2400521
… -
CRISPR 3.0: Bridge RNAs Expand Human Genome Editing Capabilities
By
–
Building on more remarkable work by @arcinstitute to markedly expand the capabilities for human genome editing ("CRISPR 3.0"). Watch our conversation just after their discovery of Bridge RNAs https://
erictopol.substack.com/p/patrick-hsu-
a-trailblazer-in-digital
… -
Generative AI Clinical Reasoning Models Fail Under Scrutiny
By
–
The performance of generative A.I. models for clinical reasoning are not holding up to increased scrutiny https://
arxiv.org/abs/2509.18234 @MSFTResearch https://
ai.nejm.org/doi/full/10.10
56/AIdbp2500120
… @NEJM_AI @AdamRodmanMD @LiamGMcCoy -
GLP-1 Drugs Show Different Weight Loss Effects in Diabetics
By
–
More than 2 decades since GLP-1 drugs were introduced, we still don't know why people with diabetes lose about half as much weight as those without diabetes at the same dose https://
nature.com/articles/s4136
6-025-01920-4
… -
AI Prior Authorization Program Raises Healthcare Concerns
By
–
What could possibly go wrong? https://
kffhealthnews.org/news/article/a
i-medicare-prior-authorization-trump-pilot-program-wiser/?utm_campaign=KHNFirstEdition&utm_medium=email&_hsenc=p2ANqtz–ea5c2MUpa_mWlasUTiUurxkRHR10Fkkw0G_9uhOnyDfAq-GCbYjieDw97IBZSdkjhkogBXEOvkQL-Y2c03U0I-t64nw&_hsmi=382232457&utm_content=382232457&utm_source=hs_email
…