I was referring specifically to colon cancer screening
@erictopol
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$100 Genome Sequencing Breakthrough Achieved by San Diego Startup
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The $100 whole human genome sequence finally reached! @ElemBio https://
sandiegouniontribune.com/2026/02/19/scr
appy-san-diego-startup-goes-toe-to-toe-with-gene-sequencing-giant-illumina/
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Large MCED AI Trial Misses Primary Endpoint Despite Promise
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142,000 participants!
The largest randomized trial of a multi-cancer early detection (MCED) test failed its primary endpoint https://
genomeweb.com/cancer/grail-f
da-plans-undeterred-after-nhs-galleri-mced-trial-misses-primary-endpoint
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Had the enrollment been risk-based instead of age 50, it would likely have been very positive. -
Clinical Trials Ongoing for AI Healthcare Application
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Yes, very likely, ongoing clinical trials are assessing it now
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FDA Approves Vagus Nerve Stimulation for Rheumatoid Arthritis Treatment
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1 minute of vagus nerve stimulation per day was recently FDA approved as a treatment for rheumatoid arthritis. A new Ground Truths podcast with @KevinJTraceyMD who pioneered this field https://
erictopol.substack.com/p/vagus-nerve-
stimulation-and-the-immune
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Medicine’s Future Pivot Toward Prevention and Aging Research
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Two of the most important recent quotes about the future direction of medicine, a pivot to prevention @Thomas_Rando @NatureAging
; Francisco Caiado and Markus Manz @ScienceMagazine -
New Science of Preventing Heart Attacks Through AI
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We can and should be doing this. Conversation with @jacobgoldstein @pushkinpods https://
pushkin.fm/podcasts/whats
-your-problem/the-new-science-of-preventing-heart-attacks
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Single molecule sequencing advances enable deeper biological interrogation
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A tour de force single molecule review @ScienceMagazine "the ongoing convergence of two foundational technologies in modern biology: sequencing and single-molecule biophysics……we are now poised to interrogate complex biological phenomena with previously
unattainable depth -
Distinguishing Heritability of Lifespan and Healthspan
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A very important paper, Ben.
I hope people will not confuse the heritability of lifespan with that of healthspan! -
AI Improves Cancer Detection Sensitivity in Radiology Trial
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The false positive rate was 1.4% in both arms of the trial
(radiologist plus AI vs 2 radiologists)
Sensitivity was 80.5% with AI, 73.8% without AI