PEP protects against age-related inflammation, puts the brake on the aging process in mice, high levels in humans correlate with low inflammation
So what is PEP, you ask? phosphoenolpyruvate, from glucose metabolism, a, master regulator, blocks cGAS-STING https://
nature.com/articles/s4358
7-026-01087-1
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@erictopol
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Grok AI Feature Now Available for Premium and Premium+ Subscribers
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Troubleshooting AI Image Generation Filters and Prompt Issues
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New @ScienceMagazine Engineering the brain's astrocytes to clear amyloid plaque! "CAR-A," in mouse model http://
science.org/doi/10.1126/sc
ience.ads3972
… http://
science.org/doi/10.1126/sc
ience.aef8451
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Grok AI Feature Available for Premium Subscribers Only
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20 years of Yamanaka stem cell factor research culminates in 2 conditional approvals for heart disease and Parkinson's disease in Japan https://
sciencedirect.com/science/articl
e/pii/S1934590926000731?viaihub
… by Shinya Yamanaka @CellStemCell https://
science.org/content/articl
e/stem-cell-therapies-come-age-two-conditional-approvals-japan
… @ScienceMagazine -
CRISPR enables causal understanding of immune system complexity
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The complexity of our immune system is daunting. But there's a path to deconvolute it and understand causal relationships. It's CRISPR. open-access @JExpMed https://
rupress.org/jem/article/22
3/3/e20241266/281510/Next-generation-CRISPR-screens-enable-causal
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AI Applications in Rare Disease and Cancer Diagnosis
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Any evidence?
I guess you haven't followed the field for diagnosis of people with rare diseases, cancer (risk and treatment), rapid neonatal sequencing for sick babies, diagnostic workup for developmental disorders, and many other areas -
Immune System Enhanced 100-to-1000-Fold Virus Protection Breakthrough
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"A heightened state of readiness led to a 100-to-1,000-fold reduction in viruses getting through the lungs and into the body."
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AI Transforms Precision Education for Physician Training
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How AI can transform precision-education for physicians "When data from many users are aggregated, these tools can generate performance ranges, revealing learning curves that could predict trajectories leading
to the best possible performance for individual trainees." -
Smart Underwear Innovation Monitors Gut Health and Flatus
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You gotta be kidding me @mims gift link https://
wsj.com/tech/personal-
tech/smart-underwear-gut-health-human-flatus-atlas-9ffa1bd7?st=mRvLAL&reflink=desktopwebshare_permalink
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GRAIL Cancer Detection Trial Fails to Meet Primary Endpoint
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On the huge randomized GRAIL trial
Front page @nytimes today @RebeccaDRobbins "The study’s goal was to show a 20 percent reduction in advanced cancers among those who got the test. That did not happen."
gift link https://
nytimes.com/2026/02/20/hea
lth/cancer-detection-test-grail.html?unlocked_article_code=1.N1A.Ivyd.lMF48TnsCUBK&smid=url-share
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