The way our immune cells age differs substantially by sex, from single-cell analysis of ~1,000 people. Implications for propensity for autoimmune diseases (women), vulnerability to cancer (men), immunosenescence and inflammaging @NatureAging
@erictopol
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AI Detects High-Risk Cancer Cell Clusters for Metastasis Prevention
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These cell clusters are up to 50X more potential to spread cancer compared with single circulating tumor cells. A very useful target for preventing metastasis, which is the predominant way cancer kills.
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AI Detects Heart Failure Risk 5 Years Before Symptoms
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AI to detect risk of heart failure 5 years ahead of symptoms via CT scan epicardial fat tissue https://
jacc.org/doi/10.1016/j.
jacc.2026.02.5116
… @JACCJournals -
AI imaging economics: nominal pricing drives healthcare adoption
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The imaging centers pay $1 to the AI companies for each patient. Their profit margin is enormous and thus nominal charge will foster implementation at scale. Today it’s close to zero
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AI Triple-Check for Mammogram Cancer Detection Implementation
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Every mammogram should be supported by 3 different AIs for improved detection of cancer, prevention, and risk of heart disease. At no cost to patients. My new @TheLancet essay reviews the evidence and the lack of implementation https://
thelancet.com/journals/lance
t/article/PIIS0140-6736(26)00659-8/fulltext
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AI breakthrough reboots B cells for autoimmune disease cure
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More success for rebooting B cells towards cure of different autoimmune diseases beyond lupus, MS and others https://
cell.com/med/abstract/S
2666-6340(26)00078-4
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Dietary Intervention With AI Models for Pediatric Brain Cancer Treatment
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Can rebooting the diet, eliminating 2 essential amino acids, help treat an aggressive brain cancer in children?
mechanism and potential established from experimental model https://
nejm.org/doi/full/10.10
56/NEJMcibr2516825
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23andMe Research Advances in Genetic AI Explainer
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Good explainer @Nature by @marilenharo https://
nature.com/articles/d4158
6-026-01107-5
… @23andMeResearch -
Optimism linked to lower dementia risk in long-term study
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No cause and effect established, but the more optimism the less dementia in >9,000 individuals with up to 14 year follow-up https://
agsjournals.onlinelibrary.wiley.com/doi/10.1111/jg
s.70392?utm_campaign=publicity_wly&utm_content=wrh_4_6_26&utm_medium=email&utm_source=muckrack&utm_term=jgs
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Genomics Predicts GLP-1 Drug Response Using AI Analysis
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Genomics of GLP-1 drug response and side effects
With genomic and demographic data it's possible to predict magnitude of weight loss response @23andMe https://
nature.com/articles/s4158
6-026-10330-z
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