Thanks Hubert. I will never forget seeing GPT-2 for the first time and thinking “if I don’t drop everything and go all in on this, I’ll regret it for the rest of my life.” So glad I did.
RESEARCH
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Dwarkesh Patel’s Podcast Coverage and AGI-Focused Narrative Analysis
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Dwarkesh is not an AGI party bro. He's been pretty diverse in how he seeks alpha from across a wide variety of industries. I enjoy the hell out of a lot of his podcasts.
This podcast though, his questions and narrative are very AGI Party takes, because I think they're very -
AI breakthrough promises major cancer treatment advancement
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L'un des cancers les plus foudroyants pourrait bientôt être vaincu. À toutes celles et ceux qui luttent aujourd'hui contre la maladie : tenez bon. Les prochains mois apporteront des signes concrets, et la décennie 2030-2040 marquera un basculement sans précédent dans l'histoire
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Six Dimensions Aligning Data Science Success Framework
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Data Science works when 6 dimensions align: Goals (value, decisions)
Methods (stats, ML/DL, A/B, viz)
People (DS+ML+Biz+Domain)
Processes (collect→clean→train→deploy→monitor)
Tech (Python/R, TF/PyTorch, cloud, SQL/NoSQL, BI)
Culture (collab, ethics, learning, -

Neural Network Disruption Through Sign-Bit Flip Attacks
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Maximal Brain Damage Without Data or Optimization Disrupting Neural Networks via Sign-Bit Flips paper: https://
huggingface.co/papers/2502.07
408
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SNR-t Bias in Diffusion Probabilistic Models Explained
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Elucidating the SNR-t Bias of Diffusion Probabilistic Models paper: https://
huggingface.co/papers/2604.16
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Frontier Models Still Outperform Open Source AI Releases
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They're almost always much worse than frontier models (no matter what anyone/benchmarks say). The last few releases have been very solid though (but I suspect frontier will pull far ahead again soon, so this won't last long).
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LLMs Struggle With Mature Scholarship Beyond Mathematical Problems
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LLMs are “ good at math style problems, where you tell them A, B and C are true, and then ask them to figure out D [but]
extremely bad at anything involving what I would call mature scholarship .. [something] like naive undergrads” –
@kareem_carr -

Jensen Huang on AI Diffusion, Policy and Real-World Ecosystems
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The Jensen + @dwarkesh_sp podcast was fantastic.
— Soumith Chintala (@soumithchintala) 20 avril 2026
Jensen is someone who understood how ecosystems work and someone who understands real-world trade, policy and controls work. And in some deeper sense how AI will actually diffuse into the world.
In this podcast, Dwarkesh came off… https://t.co/A2T9WcKQiBThe Jensen + @dwarkesh_sp podcast was fantastic. Jensen is someone who understood how ecosystems work and someone who understands real-world trade, policy and controls work. And in some deeper sense how AI will actually diffuse into the world.
In this podcast, Dwarkesh came off -
AI Transformers Cut Cancer Trial Failure Rate to 5%
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🔬 Training Transformers to solve 95% failure rate of Cancer Trials
— Latent.Space (@latentspacepod) 20 avril 2026
the AI for Science pod is back with @RonAlfa, CEO of @NOETIK_ai, and Daniel Bear, VP Research at Noetik, explaining exactly how their team of top AI x Bio researchers and engineers (shoutout @owl_posting) will… pic.twitter.com/xdyYWraTkUTraining Transformers to solve 95% failure rate of Cancer Trials the AI for Science pod is back with @RonAlfa
, CEO of @NOETIK_ai
, and Daniel Bear, VP Research at Noetik, explaining exactly how their team of top AI x Bio researchers and engineers (shoutout @owl_posting
) will