I believe that most of the big problems left to solve need to be solved with hardware + software. But occasionally, regulation and societal shifts present the opportunity for software to solve really big problems. Healthcare is one. It is an incentive problem. It's breaking
BUSINESS
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Healthcare System Incentives Critical for Gene Editing Drug Adoption
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A few months ago, @patrickc made the point that in order to take advantage of gene editing drugs, we need to change the incentives of the healthcare system. This is true for all sorts of modern scientific miracles, from cancer screens to GLP-1s.
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Thatch: Curing American healthcare through incentives and choice
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Thatch: Curing American healthcare through incentives and choice
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ICHRA: Shifting US Healthcare from Employer Plans to Individual Choice
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The American healthcare system seems hopelessly broken. It is not. Just as a small quirk in the tax code shifted retirement plans from pensions to 401(k)s, ICHRA can shift insurance from employee-sponsored to individual choice. A Deep Dive on healthcare, ICHRA, & Thatch:
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Consumer Strain and Economic Challenges Impact Tech Revenue Growth
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If you managed to break even or slightly beat Sept rev numbers YoY you should feel proud. On top of all the Meta chaos + terrible political assassination + Jimmy Kimmel situation we continue to face a consumer stretched sooooooo thin. This morning's news that August job
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Night Work Schedule Impact on Productivity and Wealth
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nighttime timeline alfa gets you far if more people stopped going to bed early for their jobs they'd be far more richer (i think)
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Meta delivery bugs and consumer confidence crisis impact
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The meta delivery bugs.
Consumer confidence down.
Meta algo change for some brands
Political assassination
Prime day hold outs A combo of a lot of bad -
NVIDIA UiPath Partnership Brings Secure Enterprise Automation
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We’re thrilled to be collaborating with UiPath to bring trusted automation to sensitive workflows. Together, we’re combining UiPath expertise with NVIDIA NIM microservices and open Nemotron models for secure, enterprise-grade AI adoption.
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Alteryx Named Leader in Snowflake Modern Marketing Data Stack
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Alteryx is named a leader in @Snowflake
’s 2026 Modern Marketing Data Stack for Analytics & BI. Together, we help teams cut manual steps, simplify workflows, and deliver secure insights at scale. Learn more: https://
ow.ly/wEI450X3OFh #AlteryxPartner -
AI Agents in Finance: 2025-2030 Evolution Forecast with PopAi
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While my assistant is on marriage leave, I drafted a short deck with this prompt using PopAi @popaiinone Slide Agent ➡️ “Create slides on predicting how AI agents can be applied to the financial industry. Analyze six major sub-sectors and create a timeline listing 15 to 20 AI agent application evolution for the financial sector between 2025 and 2030.” First generation is impressive (fact-checking AI, always). Now I can further change templates, charts, layout and more. popai.pro/ppt-share?shareKey…