excel didn’t have LLMs in the 90s (it did have some ML, which I have praised, but not that far back).
AI
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Analyzing o3, Grok 4, and Claude Code
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start with https://
open.substack.com/pub/garymarcus
/p/how-o3-and-grok-4-accidentally-vindicated?r=8tdk6&utm_medium=ios
… and my substack piece on Claude Code and then read my 2001 book The Algebraic Mind -
Claude Code and the Neurosymbolic Approach to LLM Limitations
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claude code is an immense neurosymbolic effort to ward off the failure of pure LLMs. you sir are lost.
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Technical analysis of neurosymbolic AI architecture
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it’s a klugey neurosymbolic system but its certainly neurosymbolic. it’s certainly NOT a pure neural networks, and certainly not a pure symbolic system. it is a blend. (and of course lots of symbolic systems are kluges)
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Live demonstration of AI agent-based application development
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Live at #Rev26: @DominoDataLab CEO Nick Elprin builds a working Streamlit app on stage. Data file in, natural language prompt to an agent, deployed app out. The compliance layer stays. The friction doesn't.
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AI identifying human errors in benchmark testing
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And I say irony because of the fact that we, humans, design tests to evaluate the capabilities of AI, and then it’s the AI that comes along to point out the errors made by humans in our tests.
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GPT-5.5 evaluation errors revealed in FrontierMath benchmark
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The irony. Using AI (GPT 5.5), errors have been identified that would affect 1/3 of the problems in the FrontierMath benchmark Tiers 1-4. This could represent a shift in the evaluations of AI's mathematical capabilities, which may be underestimated.
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Isomorphic Labs secures $2.1B to advance AI-driven drug discovery
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I’ve always believed the No.1 application of AI should be to improve human health.
— Demis Hassabis (@demishassabis) 12 mai 2026
That work started with AlphaFold, and now at @IsomorphicLabs with the mission to reimagine drug discovery and one day solve all disease!
We are turbocharging that goal with $2.1B in new funding. pic.twitter.com/Hvk20dHgjlI’ve always believed the No.1 application of AI should be to improve human health. That work started with AlphaFold, and now at @IsomorphicLabs with the mission to reimagine drug discovery and one day solve all disease! We are turbocharging that goal with $2.1B in new funding.
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Google Gemini Omni Agents and AI Avatars Coming Soon
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GOOGLE : A new Gemini Omni banner has been added to the web build recently. > Gemini Omni will be an Agent that can combine text, images, and videos. > Users will be able to add themselves to different scenes. As we know, AI Avatars (Likeness) are coming to Gemini as well,