Which sets up the power of bespoke cancer vaccines
@erictopol
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AI Biomarkers Enable Personalized Cancer Treatment Advances
By
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A brilliant review on the wealth of biomarkers for cancer and how they are enabling individualized treatment, improving prognosis https://
sciencedirect.com/science/articl
e/pii/S0092867424002447
… by @APassaroMD @peters_solange and colleagues @CellCellPress -
AI Improves Cancer Detection Through Whole-Body MRI Screening
By
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On whole-body MRI screening for cancer https://
economist.com/technology-qua
rterly/2024/03/27/artificial-intelligence-has-long-been-improving-diagnoses
… -
Cancer Systems Disease Review Integrates AI Analysis Perspectives
By
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A comprehensive 5★ perspective/review on cancer as a complex, systemic disease with all the hallmarks https://
cell.com/cell/fulltext/
S0092-8674(24)00175-2
… @CellCellPress by @CharlesSwanton and colleagues -
AI and Digital Biology Convergence with Daphne Koller
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There's no one better to discuss the convergence of #AI and digital biology than @DaphneKoller Our conversation on the new Ground Truths podcast
(link in profile) -
Organ Clocks Advance Biological Aging Modulation Research
By
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Organ clocks are an important advance as we move toward the potential of modulating human biological aging https://
wsj.com/health/wellnes
s/aging-biological-age-organs-health-9b6a4798?mod=Searchresults_pos9&page=1
… by @AlexLJanin This article is about @wysscoray
's outstanding work, published @Nature
, that we recently discussed https://
erictopol.substack.com/p/tony-wyss-co
ray-the-science-of-aging
… -
NHS Digital Future: AI Healthcare Transformation Vision
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Nice lede https://
nature.com/articles/s4159
1-024-02860-8
… @NatureMedicine "The 2019 Topol Review for the UK National Health Service (NHS) outlined a vision for a digital future for healthcare."
by @Sheena_Visram @njsebire Yvonne Rogers -
PD-1 Receptor Dimer Structure Offers New Autoimmune Disease Treatment
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@SciImmunology Contrary to science dogma, the programmed cell death (PD-1) receptor on immune cells exists as a dimer (not just as a monomer). Its stimulation (checkpoint agonist) may be well suited to treat/prevent autoimmune diseases https://
science.org/doi/10.1126/sc
iimmunol.ade6256
… @Elliot_Philips -
Y Chromosome Loss Triggers Epigenetic Switch in Heart Macrophages
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@NatureCVR The loss of Y chromosome in older men is associated with heart failure, but the mechanism is unknown. As determined via single-cell omics, an epigenetic switch occurs for heart macrophages to become pro-fibrotic https://
nature.com/articles/s4416
1-024-00439-7
… -
Generative AI Accelerates Fibrosis Drug to Clinical Trials
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Thanks to generative #AI, a drug that counters fibrosis (scarring), and possibly modulates the tissue aging process, with its mechanism elucidated, has been rapidly advanced to clinical trials for IPF https://
nature.com/articles/s4158
7-024-02143-0
… @NatureBiotech @biogerontology @InSilicoMeds