Our new @NatureMedicine paper proposing a path for better, dynamic evaluation of large language models for patient care https://
nature.com/articles/s4159
1-026-04252-6
… CES-clinical environment simulator @pranavrajpurkar
@erictopol
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Dynamic LLM Evaluation Framework for Clinical Patient Care Applications
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Clinical Trials Results Pending AI Healthcare Breakthroughs
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I just replied. Lots of potential pending results of clinical trials.
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CAC versus CCTA: Selective Clinical Applications in Cardiology
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CAC only. CCTA has great use in select individuals.
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Cancer Vaccines Show Promise Against Refractory Cancers
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Cancer vaccines are showing marked efficacy vs refractory cancers and are going to be part of the future Rx armamentarium. Beyond that, ultimately, for prevention in high-risk individuals.
A new stellar review @NatureMedicine https://
nature.com/articles/s4159
1-026-04241-9
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Cerebral Microhemorrhages Risk with Amyloid Antibody Therapy
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100 brain microhemorrhages in a patient with cerebral amyloid angiopathy and 2 copies of APOE4 after amyloid antibody therapy https://
cureus.com/articles/47297
1-one-hundred-cerebral-microhemorrhages-rethinking-cerebral-amyloid-angiopathy-in-the-era-of-amyloid-targeted-antibodies#!/
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HSV-1 Reactivation Linked to Aging and Dementia Risk
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The reactivation of herpes simplex virus (HSV-1, not only herpes zoster) may be tied to accelerated aging and dementia, and account in part for the mechanism of Shingrix vaccine''s protection @WIRED
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Jensen Huang’s admission redefines AI’s practical utility timeline
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@ScienceMagazine An exciting new approach vs pancreatic cancer: "cancer interception"
Considered ubiquitous, the pancreas in healthy adults has hundreds of PanINs of microscopic premalignant cancer that can be regressed in the experimental model https://
science.org/doi/10.1126/sc
ience.aef6665
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Advisory Jury in Musk-OpenAI Trial Focuses on Liability, Not Damages
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What is the significance of microbes in tumors, a field mired in controversy? https://
cell.com/cancer-cell/ab
stract/S1535-6108(26)00109-1
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The Singularity We Wanted Versus The Circularity We Got
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Now achieved with nanoparticles in vivo, in the experimental model, which could be a big step forward https://
science.org/doi/10.1126/sc
iadv.adz1722
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Brockman’s statements on deceiving Musk and OpenAI’s early contributions
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More on the study results and interpretationhttps://t.co/IAeO7zFL5U
— Eric Topol (@EricTopol) 11 mars 2026More on the study results and interpretation