The full process took about 2.5 months, plus another half month for human chemists to write up the results. This is an early example of frontier models supporting more of the scientific research loop: reviewing studies, proposing hypotheses, designing experiments, interpreting
INNOVATION
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GPT-5.4 and human chemists collaborate on full research workflow
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GPT-5.4 reviewed scientific literature, generated and ranked research proposals, helped design experiments, analyzed results, and proposed follow-up studies. Human chemists steered the work, selected proposals for testing, and validated the final result.
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GPT-5.4 and Maria AI improve drug discovery reaction
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GPT-5.4 helped drive a medicinal chemistry project from literature review to a validated experimental result.
— OpenAI (@OpenAI) 17 juin 2026
Paired with https://t.co/gcDaph8b2B’s Maria AI and specialized lab, the model proposed an unexpected way to improve a widely used reaction in drug discovery. pic.twitter.com/KmyBlHLX8yGPT-5.4 helped drive a medicinal chemistry project from literature review to a validated experimental result. Paired with http://
Molecule.one’s Maria AI and specialized lab, the model proposed an unexpected way to improve a widely used reaction in drug discovery. -
GitHub COO interviewed on agent-created pull requests surge
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GitHub has a front-row seat to how code is changing now that everyone—and their army of agents—can ship code. In March alone, agents created 17 million pull requests on the platform.
— Dan Shipper 📧 (@danshipper) 17 juin 2026
That’s why I was thrilled @hammer_mt was on hand to interview @github COO @kdaigle at Microsoft… pic.twitter.com/bwMYCgLOW1GitHub has a front-row seat to how code is changing now that everyone—and their army of agents—can ship code. In March alone, agents created 17 million pull requests on the platform. That’s why I was thrilled @hammer_mt was on hand to interview @github COO @kdaigle at Microsoft
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Altman: AI debate over, powerful systems to reshape economy and science
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Sam Altman made a notable statement at the G7 summit. Altman said that the debate over whether AI is useful is over, arguing that far more powerful AI systems will emerge in the coming years. He also suggested that AI could reshape both the global economy and scientific
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Scobleizer: First real-time world models demonstrated
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Sorry, totally disagree there. Game engines and robotics didn't use world models until recently. And he certainly was the first to show real time world models.
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An AI-native email platform integrated with Codex and MCP agents
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An AI native email platform built from the ground up to run entirely from inside Codex, ChatGPT, and any AI agent via MCP.
— Robert Scoble (@Scobleizer) 17 juin 2026
Your agents now have their own email.
And it learns and gets better over time. https://t.co/UPRwAKxEw3An AI-native email platform built from the ground up to run entirely from inside Codex, ChatGPT, and any AI agent via MCP. Your agents now have their own email. And it learns and gets better over time.
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Massive capability gains from models if you know how
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I'm not sure if it'll last (I go back and forth), but today, there's massive capability gains you can pull out of the models if you know what you're doing.
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Databricks AI Platform unveils ML engineering, deep learning, and real-time inference advances
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New capabilities across the Databricks AI Platform help ML teams tackle some of the most challenging parts of building production machine learning systems.
— Databricks (@databricks) 17 juin 2026
We're announcing advances in ML engineering, deep learning, and real-time inference:
• Genie Code now comes with upgraded… pic.twitter.com/OusVzJPILTNew capabilities across the Databricks AI Platform help ML teams tackle some of the most challenging parts of building production machine learning systems. We're announcing advances in ML engineering, deep learning, and real-time inference: • Genie Code now comes with upgraded
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Satya Nadella discusses enterprise context, AI innovation, and value creation
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@satyanadella
, Chairman and CEO of @Microsoft
, on the importance of enterprise context, the pace of innovation today, and the future of value creation with AI. Nadella joined @alighodsi
, co-founder and CEO of Databricks for a discussion shared with attendees at #DataAISummit on