We need Microtubule/Acc urgently*** Human intelligence is rooted in the cellular efficiency of pyramidal neurons within the prefrontal cortex and hippocampal CA1. These regions show high expression of genetic variants associated with superior cognitive ability. Quantitative morphology reveals that high-IQ individuals possess neurons with larger dendritic trees. This architecture allows for superior synaptic integration and signal amplification. Furthermore, these neurons exhibit faster action potential conduction velocities, enabling more rapid information processing across neural networks. Microtubule-associated proteins (MAPs) underpin these traits. By stabilizing the cytoskeleton, MAPs facilitate the rapid transport required for high-speed synaptic communication. This structural efficiency defines the cellular engine of superior cognition. frontiersin.org/journals/hum…

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