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Soft Decomposability for Efficient Scientific Design in Proteins

Our new ICLR paper on leveraging “soft decomposability” of design spaces (eg protein sequence) wrt a target property (eg enzymatic activity) in order to more efficiently search through the design space. Active site vs. scaffold, for eg. @jamesbowden_ joint with @svlevine James Bowden (@jamesbowden_) I'm excited to share our ICLR paper on how leveraging decomposability can enable more efficient scientific design, with @jlistgarten and @svlevine. We were motivated by protein design in particular. Check out the blog post: james-bowden.github.io/dado/. — https://nitter.net/jamesbowden_/status/2035457915428233479#m

→ View original post on X — @berkeley_ai, 2026-03-21 21:34 UTC

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